Endocrine Abstracts

Context: Gap junction intercellular communication (GJIC) and its constructed protein Connexin (Cx) participates in cell apoptosis and tumorigenesis. Our clinical studies demonstrated that a levonorgestrel (LNG)-releasing intrauterine system can reverse atypical endometrial hyperplasia.Objective: This study assesses whether LNG exerts anti-proliferation effects on human endometrial cells through changes in the GJIC function and Cx43 expression.<p clas...